The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Jun. 19, 2007
David Alsop, Newton, MA (US);
Elena Vinogradov, Boston, MA (US);
Aaron K. Grant, Allston, MA (US);
Robert E. Lenkinski, Boston, MA (US);
David Alsop, Newton, MA (US);
Elena Vinogradov, Boston, MA (US);
Aaron K. Grant, Allston, MA (US);
Robert E. Lenkinski, Boston, MA (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Abstract
In one aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided. The method includes introducing an imaging agent into the subject, the imaging agent including a compound having at least one hyperpolarized nucleus having a T.sub.1 greater than 15 seconds and a water-octanol partition coefficient between −1 and 1, providing at least one excitation signal to the region of interest, the at least one excitation signal configured to invoke a nuclear magnetic resonance (NMR) effect at least in the introduced imaging agent, and detecting an NMR signal emitted by the region of interest in response to the at least one excitation signal. In another aspect, the imaging agent includes a carbon-13 enriched alcohol.