The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2013
Filed:
Jan. 28, 2012
Amy E. Palmer, Boulder, CO (US);
Ralph Jimenez, Boulder, CO (US);
Kevin Dean, Lafayette, CO (US);
Jennifer Lubbeck, Boulder, CO (US);
Lloyd M. Davis, Tullahoma, TN (US);
Amy E. Palmer, Boulder, CO (US);
Ralph Jimenez, Boulder, CO (US);
Kevin Dean, Lafayette, CO (US);
Jennifer Lubbeck, Boulder, CO (US);
Lloyd M. Davis, Tullahoma, TN (US);
The Regents of the University of Colorado, Denver, CO (US);
University of Tennessee Research Foundation, Knoxville, TN (US);
National Institute of Standards and Technology, Gaithersburg, MD (US);
Abstract
Devices and methods for screening emissive properties of a cell, such as the resistance to photobleaching or other photophysical property. In one example, a device may include a microfluidic reservoir having at least an input channel for receiving the cell, a main channel fluidly coupled with the input channel, at least a first output channel and a second output channel, the first and second output channels fluidly coupled with the main channel; and a multibeam interrogation section generating a plurality of light beams impinging upon the main channel of the microfluidic reservoir. As a cell passes from the input channel through the main channel of the microfluidic reservoir, the cell is exposed to the plurality of light beams thereby generating emissions that are received by a signal processing section. A cell trapping section selectively diverts the cell to the second output channel if the cell contains desired emissive properties.