The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2013
Filed:
Dec. 14, 2011
Applicants:
Didier Philippe Robert Schils, Loupoigne, BE;
Alfred Elisabeth Stappers, Oud-Turnhout, BE;
Inventors:
Didier Philippe Robert Schils, Loupoigne, BE;
Alfred Elisabeth Stappers, Oud-Turnhout, BE;
Assignee:
Tibotec Pharmaceuticals Ltd., Eastgate Village, Eastgate—Little Island, Cork, IE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/47 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to a process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)-amino]benzonitrile (I) starting from a 4-oxo-1,6-dihydro-pyrimidinylcarboxylic acid ester (II) or starting from a guanidine derivative which is reacted with an alkoxy-methylene malonic acid ester to an ester (II) which is converted to (I), which reaction sequence may be a one-pot procedure.