The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2013
Filed:
Mar. 02, 2010
Jerome W. Kosmeder, Tucson, AZ (US);
Mark Lefever, Tucson, AZ (US);
Donald Johnson, Tucson, AZ (US);
Michael Farrell, Tucson, AZ (US);
Zhanna Zhilina, Oro Valley, AZ (US);
Christopher Bieniarz, Tucson, AZ (US);
Jerome W. Kosmeder, Tucson, AZ (US);
Mark Lefever, Tucson, AZ (US);
Donald Johnson, Tucson, AZ (US);
Michael Farrell, Tucson, AZ (US);
Zhanna Zhilina, Oro Valley, AZ (US);
Christopher Bieniarz, Tucson, AZ (US);
Ventana Medical Systems, Inc., Tucson, AZ (US);
Abstract
A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more specific binding moieties that bind specifically to two or more different targets. The two or more specific binding moieties are conjugated to different haptens, and at least one of the haptens is an oxazole, a pyrazole, a thiazole, a nitroaryl compound other than dinitrophenyl, a benzofurazan, a triterpene, a urea, a thiourea, a rotenoid, a coumarin, a cyclolignan, a heterobiaryl, an azo aryl, or a benzodiazepine. The sample is contacted with two or more different anti-hapten antibodies that can be detected separately. The two or more different anti-hapten antibodies may be conjugated to different detectable labels.