The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2013

Filed:

Jul. 03, 2008
Applicants:

Josef Bencsik, Longmont, CO (US);

James F. Blake, Longmont, CO (US);

James M. Graham, Longmont, CO (US);

Martin F. Hentemann, Lafayette, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Ian S. Mitchell, Lafayette, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Keith L. Spencer, Lyons, CO (US);

Dengming Xiao, Longmont, CO (US);

Rui Xu, Longmont, CO (US);

Mike Welch, Westminster, CO (US);

Jun Liang, Palo Alto, CA (US);

Brian S. Safina, Redwood City, CA (US);

Inventors:

Josef Bencsik, Longmont, CO (US);

James F. Blake, Longmont, CO (US);

James M. Graham, Longmont, CO (US);

Martin F. Hentemann, Lafayette, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Ian S. Mitchell, Lafayette, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Keith L. Spencer, Lyons, CO (US);

Dengming Xiao, Longmont, CO (US);

Rui Xu, Longmont, CO (US);

Mike Welch, Westminster, CO (US);

Jun Liang, Palo Alto, CA (US);

Brian S. Safina, Redwood City, CA (US);

Assignees:

Array Biopharma, Inc., Boulder, CO (US);

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/496 (2006.01); C07D 413/14 (2006.01); C07D 239/70 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 29/00 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of Formula (I), including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.


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