The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2013

Filed:

Jul. 02, 2009
Applicants:

Hisashi Takahashi, Tokyo, JP;

Satoshi Komoriya, Tokyo, JP;

Takahiro Kitamura, Tokyo, JP;

Takashi Odagiri, Tokyo, JP;

Hiroaki Inagaki, Tokyo, JP;

Toshifumi Tsuda, Tokyo, JP;

Kiyoshi Nakayama, Tokyo, JP;

Makoto Takemura, Tokyo, JP;

Kenichi Yoshida, Tokyo, JP;

Rie Miyauchi, Tokyo, JP;

Masatoshi Nagamochi, Tokyo, JP;

Inventors:

Hisashi Takahashi, Tokyo, JP;

Satoshi Komoriya, Tokyo, JP;

Takahiro Kitamura, Tokyo, JP;

Takashi Odagiri, Tokyo, JP;

Hiroaki Inagaki, Tokyo, JP;

Toshifumi Tsuda, Tokyo, JP;

Kiyoshi Nakayama, Tokyo, JP;

Makoto Takemura, Tokyo, JP;

Kenichi Yoshida, Tokyo, JP;

Rie Miyauchi, Tokyo, JP;

Masatoshi Nagamochi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/10 (2006.01); C07D 498/06 (2006.01); A61K 31/4709 (2006.01); A61K 31/5383 (2006.01);
U.S. Cl.
CPC ...
Abstract

A quinolone synthetic antibacterial agent having excellent properties as a medicine is provided, which has strong antibacterial activity not only to Gram-negative bacteria but also to Gram-positive cocci that have low sensitivity to quinolone antibacterial agents, and which exhibits high safety and excellent pharmacokinetics. A compound represented by the formula (I) or a salt thereof, or a hydrate thereof. Specifically, a quinolone derivative of the formula (I) wherein substituents R6 and R7 taken together with the carbon atoms to which they are bonded form a cyclic structure which may contain an oxygen atom as a ring constituent atom, the cyclic structure forming a 5-4, 5-5, or 5-6 fused bicyclic pyrrolidinyl substituent, the substituent being bonded to a quinolone mother skeleton Q containing a pyridobenzoxazine structure.


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