The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2013
Filed:
Jul. 06, 2010
Applicants:
Chengcheng Zhang, Arlington, MA (US);
Harvey Lodish, Brookline, MA (US);
Inventors:
Chengcheng Zhang, Arlington, MA (US);
Harvey Lodish, Brookline, MA (US);
Assignee:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Hematopoietic stem cells and methods for ex vivo expansion of hematopoietic stem cells are provided. The methods comprise culturing the cells in a media containing an effective amount insulin-like growth factor(IGF), fibroblast growth factor (FGF), thrombopoietin (TPO), and stem cell factor (SCF), under conditions sufficient for expansion of said cells. Methods for identifying expanded hematopoeitc stem cells and kits for ex vivo expansion of hematopoietic stem cells are also provided.