The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2013

Filed:

Apr. 29, 2005
Applicants:

Sten Braesch-andersen, Nacka Strand, SE;

Staffan Paulie, Nacka Strand, SE;

Inventors:

Sten Braesch-Andersen, Nacka Strand, SE;

Staffan Paulie, Nacka Strand, SE;

Assignee:

Mabtech AB, Nacka Strand, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a method for detecting the production of one or more analytes by cells in a sample. The method uses one or more immobilized binding proteins to capture one or more analytes released from cells. The, or each, binding protein is localized at one or more discrete locations on a solid surface within a well. Cells are introduced into the well and cultured under conditions suitable for release of the analyte(s) and for binding of the analyte(s) to the binding protein(s). Restricting the binding protein(s) to one or more discrete locations within the well, rather than coating the entire surface of the well, results in increased sensitivity of the assay.


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