The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2013

Filed:

Oct. 20, 2006
Applicants:

Esther H. Chang, Potomac, MD (US);

Kathleen F. Pirollo, Rockville, MD (US);

Inventors:

Esther H. Chang, Potomac, MD (US);

Kathleen F. Pirollo, Rockville, MD (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/12 (2006.01); A61K 49/04 (2006.01); A61K 49/06 (2006.01); A61K 49/18 (2006.01); A61K 39/00 (2006.01); A61K 9/127 (2006.01); A61K 35/00 (2006.01); A61K 35/04 (2006.01); A61B 5/055 (2006.01); A61B 8/00 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is in the fields of drug delivery, cancer treatment and diagnosis and pharmaceuticals. This invention provides a method of making antibody- or antibody fragment-targeted immunoliposomes for the systemic delivery of molecules to treat and image diseases, including cancerous tumors. The invention also provides immunoliposomes and compositions, as well as methods of imaging various tissues. The liposome complexes are useful for encapsulation of imaging agents, for example, for use in magnetic resonance imaging. The specificity of the delivery system is derived from the targeting antibodies or antibody fragments.


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