The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
May. 14, 2010
Lucio Claudio Rovati, Monza, IT;
Astrid Nagell, Hamburg, DE;
Aguirre Jaime Xiol, Barcelona, ES;
Prous Santiago Rull, Barcelona, ES;
Ralf-torsten Pohl, Speyer, DE;
Ulrich Mengs, Rösrath, DE;
Lucio Claudio Rovati, Monza, IT;
Astrid Nagell, Hamburg, DE;
Aguirre Jaime Xiol, Barcelona, ES;
Prous Santiago Rull, Barcelona, ES;
Ralf-Torsten Pohl, Speyer, DE;
Ulrich Mengs, Rösrath, DE;
Euromed S.A., Mottet del Valles, ES;
Abstract
The invention relates to a method for the preparation of amorphous silibinin (or its synonyms: silybin or silibin) derived from a milk thistle fruit extract having an increased release rate and improved absorbability or bioavailability, and to the use of amorphous silibinin for the treatment or prevention of liver diseases, preferably for the treatment of viral hepatitis, e.g. hepatitis B or C, in particular in a patient who will undergo or has undergone liver transplantation. Preferably, the amorphous silibinin is adapted for oral administration.