The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Sep. 14, 2012
John E. Park, Warthausen, DE;
Cornelia Dorner-ciossek, Warthausen, DE;
Stefan Hoerer, Biberach, DE;
Lothar Kussmaul, Schemmerhofen, DE;
Martin Lenter, Neu-Ulm, DE;
Katharina Zimmermann, Biberach, DE;
Gerald Beste, Ghent, BE;
Toon Laeremans, Dworp, BE;
Pascal Merchiers, Kasterlee, BE;
JO Vercammen, Sint-Pieters-Leeuw, BE;
John E. Park, Warthausen, DE;
Cornelia Dorner-Ciossek, Warthausen, DE;
Stefan Hoerer, Biberach, DE;
Lothar Kussmaul, Schemmerhofen, DE;
Martin Lenter, Neu-Ulm, DE;
Katharina Zimmermann, Biberach, DE;
Gerald Beste, Ghent, BE;
Toon Laeremans, Dworp, BE;
Pascal Merchiers, Kasterlee, BE;
Jo Vercammen, Sint-Pieters-Leeuw, BE;
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease.