The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Sep. 01, 2008
Hans Jürgen Wester, Ilmmünster, DE;
Horst Kessler, Garching, DE;
Oliver Demmer, München, DE;
Ingrid Dijkgraaf, Neubiberg, DE;
Hans Jürgen Wester, Ilmmünster, DE;
Horst Kessler, Garching, DE;
Oliver Demmer, München, DE;
Ingrid Dijkgraaf, Neubiberg, DE;
Technische Universitat Munchen, Munich, DE;
Abstract
A compound, or a pharmaceutically acceptable salt or ester thereof, comprises the structure: [(P1-S1)-L-(S2-P2)]wherein: P1 and P2, which may be the same or different, are cyclic oligopeptide moieties, at least one of P1 and P2 having the motif B-Arg or B-(Me) Arg within the cyclic moiety, wherein B is a basic amino acid, a derivative thereof, or phenylalanine or a derivative thereof; S1 and S2 are spacer groups, which may be the same or different; L is a linker moiety containing at least two functional groups for attachment of the cyclic oligopeptides or spacer groups; n and q are independently 0 or 1; p and r are independently integers of 1 or more; and t is an integer of 1 or more, provided that, when t, p or r is greater than 1, the cyclic oligopeptide moiety, spacer group and/or the value of j or q may be the same or different between the multiple (P1-S1) moieties or multiple (S2-P2) moieties.