The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Mar. 09, 2010
Hanbin Shan, Shanghai, CN;
Peng Zhang, Shanghai, CN;
Zhedong Yuan, Shanghai, CN;
Xudong Jiang, Shanghai, CN;
Yu Huang, Shanghai, CN;
Hubo Wang, Shanghai, CN;
Xufeng Cao, Shanghai, CN;
Xingdong Cheng, Shanghai, CN;
Xiong Yu, Shanghai, CN;
Hanbin Shan, Shanghai, CN;
Peng Zhang, Shanghai, CN;
Zhedong Yuan, Shanghai, CN;
Xudong Jiang, Shanghai, CN;
Yu Huang, Shanghai, CN;
Hubo Wang, Shanghai, CN;
Xufeng Cao, Shanghai, CN;
Xingdong Cheng, Shanghai, CN;
Xiong Yu, Shanghai, CN;
Les Laboratories Servier, Suresnes Cedex, FR;
Abstract
The invention provides a new crystalline form of agomelatine, preparation and use thereof. The X-ray powder diffraction diagram of the agomelatine crystalline form shows main peaks at the diffraction angles 2θ 11.13°, 11.82°, 17.49°, 18.29°, 19.48°, 19.72°, 20.50°, 21.76°, 22.54°, 22.97°, 24.56°, 25.36°, 27.16° and 31.93°. Said new crystalline form is characterized by high purity, stability and good reproducibility, and thus is advantageous for the pharmaceutical formulation. In addition, the stability and solubility of said crystalline form are also superior over the several existing crystalline forms.