The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Nov. 13, 2009
Gerard Karsenty, New York, NY (US);
Patricia F. Ducy, New York, NY (US);
Vijay Kumar Yadav, Cambridge, GB;
Donald Landry, New York, NY (US);
Shi-xian Deng, White Plains, NY (US);
Gerard Karsenty, New York, NY (US);
Patricia F. Ducy, New York, NY (US);
Vijay Kumar Yadav, Cambridge, GB;
Donald Landry, New York, NY (US);
Shi-Xian Deng, White Plains, NY (US);
The Trustees of Columbia University in the City of New York, New York, NY (US);
Abstract
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.