The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Apr. 27, 2012
Augustus O Okhamafe, Concord, CA (US);
Joyce Chou, El Cerrito, CA (US);
Rampurna Gullapalli, San Bruno, CA (US);
Eric Harwood, Seattle, WA (US);
David Ryckman, San Diego, CA (US);
Shuguang Zhu, San Diego, CA (US);
Xiao Shang, Bellevue, WA (US);
Augustus O Okhamafe, Concord, CA (US);
Joyce Chou, El Cerrito, CA (US);
Rampurna Gullapalli, San Bruno, CA (US);
Eric Harwood, Seattle, WA (US);
David Ryckman, San Diego, CA (US);
Shuguang Zhu, San Diego, CA (US);
Xiao Shang, Bellevue, WA (US);
Novartis AG, Basel, CH;
Abstract
The present invention relates to non-hydrate crystalline forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one lactic acid salts, solid pharmaceutical formulations containing the same and methods of use. The present invention also relates to crystalline hydrates of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-l-yl)-lH-benzimidazol-2-yl]-lH-quinolin-2-one lactic acid salts, pharmaceutical formulations containing the same and methods of use related thereto. The present invention further relates to crystalline solvates of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-l-yl)-lH-benzimidazol-2-yl]-lH-quinolin-2-one lactic acid salts.