The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2013

Filed:

Sep. 26, 2012
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Alastair James Hodges, Saffron Walden, GB;

Mizio Matteucci, Saffron Walden, GB;

Andrew Sharpe, Saffron Walden, GB;

Minghua Sun, Burlingame, CA (US);

Xiaojing Wang, Foster City, CA (US);

Vickie H. Tsui, Burlingame, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01); A61K 31/44 (2006.01); A61K 31/415 (2006.01); A01N 43/40 (2006.01); A01N 43/56 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 403/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is thiazolyl, pyrazinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.


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