The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2013

Filed:

Jan. 31, 2012
Applicants:

Yali Wang, Jiangsu, CN;

Aifeng Lü, Jiangsu, CN;

Changan Sun, Jiangsu, CN;

Hengli Yuan, Jiangsu, CN;

Inventors:

Yali Wang, Jiangsu, CN;

Aifeng Lü, Jiangsu, CN;

Changan Sun, Jiangsu, CN;

Hengli Yuan, Jiangsu, CN;

Assignee:

Jiangsu Hansoh Pharmaceuticals Co., Ltd., Lianyungang, Jiangsu, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/26 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/12 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity.X-X-Glu-Gly-Thr-Phe-Thr-Ser-Asp-X-Ser-X-X-X-Glu-X-X-Ala-X-X-X-Phe-Ile-X-Trp-Leu-X-X-X-X-X-X-X-X-X-X-X-X-X-Lys  Formula (I)—SEQ ID NO: 238


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