The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Feb. 24, 2010
Applicant:
Tina K. Van Dyk, Wilmington, DE (US);
Inventor:
Tina K. Van Dyk, Wilmington, DE (US);
Assignee:
Butamax(TM) Advanced Biofuels LLC, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 15/00 (2006.01); C12P 7/16 (2006.01); C07K 14/00 (2006.01); C07H 21/00 (2006.01); C12N 9/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Increasing tolerance to butanol in yeast has been accomplished by decreasing activity of Pdr5p encoded by an endogenous PDR5 gene. A deletion mutation of the PDR5 gene led to improved growth yield in the presence of butanol. Yeast cells with reduced Pdr5p activity, or other multidrug resistance ATP-binding cassette transporter protein activity encoded by CDR1 or BFR1, and a butanol biosynthetic pathway may be used for improved butanol production.