The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2013

Filed:

Jul. 30, 2010
Applicants:

Yossef Raviv, Rockville, MD (US);

Julie M. Belanger, Frederick, MD (US);

Mathias Viard, Frederick, MD (US);

Robert Blumenthal, Bethesda, MD (US);

Julian W. Bess, Jr., Frederick, MD (US);

Inventors:

Yossef Raviv, Rockville, MD (US);

Julie M. Belanger, Frederick, MD (US);

Mathias Viard, Frederick, MD (US);

Robert Blumenthal, Bethesda, MD (US);

Julian W. Bess, Jr., Frederick, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 7/06 (2006.01); C12N 13/00 (2006.01); A61P 31/12 (2006.01); A61P 37/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention involves inactivation of viral populations by treating the viral populations with a compound to crosslink proteins in the viral membrane, UV irradiation and further inactivation of the viruses using detergent(s). According to the invention, this method preserves the native structure of viral epitopes so that the inactivated viral preparations can be used in immunological compositions that will inhibit and/or prevent viral infection when administered to an animal.


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