The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2013
Filed:
Aug. 26, 2011
Applicants:
David R. Clemmons, Chapel Hill, NC (US);
Laura A. Maile, Chapel Hill, NC (US);
Inventors:
David R. Clemmons, Chapel Hill, NC (US);
Laura A. Maile, Chapel Hill, NC (US);
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/38 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method of inhibiting cellular activation by insulin-like growth factor-1 (IGF-1) in a subject in need thereof (e.g., a subject afflicted with cancer, atherosclerosis, diabetic retinopathy or other disease) comprises administering an antagonist that inhibits the binding of IAP to SHPS-1 to the subject in an amount effective to inhibit cellular activation by IGF-1. Compounds and compositions for carrying out such methods are also described.