The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2013

Filed:

Jun. 25, 2013
Applicant:

Virginia Commonwealth University, Richmond, VA (US);

Inventors:

Umesh R. Desai, Glen Allen, VA (US);

Brian L. Henry, Pittsburgh, PA (US);

Aiye Liang, North Charleston, SC (US);

Jay Thakkar, Denver, CO (US);

John B. Mangrum, Richmond, VA (US);

Ivo Torres Filho, San Antonio, TX (US);

Bruce D. Spiess, Manakin-Sabot, VA (US);

Masahiro Sakagami, Richmond, VA (US);

Bhawana Saluja, North Bethesda, MD (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/12 (2006.01); A61K 31/185 (2006.01); A61K 31/192 (2006.01); A61K 31/343 (2006.01); A61K 31/255 (2006.01); C07C 305/24 (2006.01); C07D 307/80 (2006.01); C07D 307/84 (2006.01); C07D 407/14 (2006.01); A61P 7/02 (2006.01); A61P 29/00 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Cinnamic acid-based oligomers and therapeutic uses thereof are provided. The oligomers are used as anti-inflammation agents, inhibitors of elastase and anti-oxidants, and in some cases (e.g. the treatment of lung disorders such as lung cancer) all three activities are simultaneously beneficial. Subsets of the oligomers (e.g. β-O4 and β-5 trimers and tetramers) are used as anticoagulants.


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