The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2013
Filed:
Nov. 16, 2009
Ernest Fraenkel, Cambridge, MA (US);
Shao-shan Carol Huang, Cambridge, MA (US);
David R. Karger, Cambridge, MA (US);
Laura Riva, Cambridge, MA (US);
Esti Yeger-lotem, Misgav, IL;
Ernest Fraenkel, Cambridge, MA (US);
Shao-Shan Carol Huang, Cambridge, MA (US);
David R. Karger, Cambridge, MA (US);
Laura Riva, Cambridge, MA (US);
Esti Yeger-Lotem, Misgav, IL;
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
A method for identifying a mechanism associated with a cellular response includes identifying molecules participating in the cellular response; accessing a database containing information characterizing molecular interactions; determining pathways connecting the identified molecules participating in the cellular response; and solving an optimization problem that includes determining a subset of the molecules and interactions having a minimum aggregate cost. The pathways include, nodes, each representing a molecule, and edges, each connecting a respective pair of nodes and representing an interaction between a respective pair of molecules represented by the respective pair of nodes. Nodes from a subset of nodes represent molecules identified as participating in the cellular response.