The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2013
Filed:
Jul. 29, 2009
Donmienne Doen Mun Leung, San Diego, CA (US);
Peng Luan, Fishers, IN (US);
Ying Tang, San Diego, CA (US);
Derrick Ryan Witcher, Fishers, IN (US);
Pia Pauliina Yachi, San Diego, CA (US);
Donmienne Doen Mun Leung, San Diego, CA (US);
Peng Luan, Fishers, IN (US);
Ying Tang, San Diego, CA (US);
Derrick Ryan Witcher, Fishers, IN (US);
Pia Pauliina Yachi, San Diego, CA (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Monoclonal antibodies are provided that bind to the N-terminus of human hepcidin-25 and are characterized as having high affinity and selectivity for the polypeptide. The antibodies of the invention are useful for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment of various disorders, such as anemia, in a human subject. The antibodies of the invention are also useful as analytical tools, such as in sandwich ELISA.