The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2013

Filed:

May. 15, 2012
Applicants:

Alfredo C. Castro, Winchester, MA (US);

Kristopher M. Depew, Acton, MA (US);

Michael J. Grogan, Winchester, MA (US);

Charles W. Johannes, Newbury, MA (US);

Edward B. Holson, Newton Highlands, MA (US);

Brian T. Hopkins, Newton, MA (US);

Gregg F. Keaney, Belmont, MA (US);

Nii O. Koney, New York, NY (US);

Tao Liu, Ashland, MA (US);

David A. Mann, Madison, WI (US);

Marta Nevalainen, Quincy, MA (US);

Stephane Peluso, Somerville, MA (US);

Lawrence Blas Perez, Hopkinton, MA (US);

Daniel A. Snyder, Somerville, MA (US);

Thomas T. Tibbitts, Westford, MA (US);

Inventors:

Alfredo C. Castro, Winchester, MA (US);

Kristopher M. Depew, Acton, MA (US);

Michael J. Grogan, Winchester, MA (US);

Charles W. Johannes, Newbury, MA (US);

Edward B. Holson, Newton Highlands, MA (US);

Brian T. Hopkins, Newton, MA (US);

Gregg F. Keaney, Belmont, MA (US);

Nii O. Koney, New York, NY (US);

Tao Liu, Ashland, MA (US);

David A. Mann, Madison, WI (US);

Marta Nevalainen, Quincy, MA (US);

Stephane Peluso, Somerville, MA (US);

Lawrence Blas Perez, Hopkinton, MA (US);

Daniel A. Snyder, Somerville, MA (US);

Thomas T. Tibbitts, Westford, MA (US);

Assignee:

Infinity Discovery, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/42 (2006.01); C07D 261/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.


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