The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2013
Filed:
Sep. 07, 2010
Jeffrey L. Goldberg, Miami, FL (US);
Vance P. Lemmon, Miami, FL (US);
John Bixby, Miami, FL (US);
Darcie Moore, Zurich, CH;
Murray Blackmore, Miami, FL (US);
Jeffrey L. Goldberg, Miami, FL (US);
Vance P. Lemmon, Miami, FL (US);
John Bixby, Miami, FL (US);
Darcie Moore, Zurich, CH;
Murray Blackmore, Miami, FL (US);
University of Miami, Miami, FL (US);
Abstract
This invention relates, to a method for promoting CNS axon regeneration, comprising (1) inhibiting the expression or activity in a neuron of one or more of the members of the Krüppel-like transcription factor (KLF) family that suppress axon growth (e.g., KLF 1, 2, 3, 4, 5, 9,12, 13, 14, 15 and/or 16), and/or (2) stimulating the expression or activity in a neuron of one or more of the members of the KLF family that promote axon growth (e.g., KLF 6 and/or 7).