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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8609137 B1

PDFFull Text
Date of Patent:
Dec. 17, 2013

Filed:

Apr. 22, 2011

Soft capsule of butylphthalide and a process for preparing the same

Applicants:

Jianqing LI, Shijiazhuang, CN;

Min Bai, Shijiazhuang, CN;

Wenmin Guo, Shijiazhuang, CN;

Surui Chen, Shijiazhuang, CN;

Liyun Liu, Shijiazhuang, CN;

Guirong Zhou, Shijiazhuang, CN;

Inventors:

Jianqing Li, Shijiazhuang, CN;

Min Bai, Shijiazhuang, CN;

Wenmin Guo, Shijiazhuang, CN;

Surui Chen, Shijiazhuang, CN;

Liyun Liu, Shijiazhuang, CN;

Guirong Zhou, Shijiazhuang, CN;

Assignees:

CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Hebei, CN;

CSPC NBP Pharmaceutical Co., Ltd., Hebei, CN;

Attorneys:

Edwards Wildman Palmer LLP

Ralph A. Loren, Esq.

Richard B. Emmons

Primary Examiner:

Nissa Westerberg

Int. Cl.
CPC ...
A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses a novel soft capsule of butylphthalide and a process for preparing the same. The soft capsule of butylphthalide is composed of a capsule wall material and a drug-containing oil, wherein the drug-containing oil is essentially composed of butylphthalide and a vegetable oil as the diluent in a weight ratio of about 1:0˜10. The capsule wall material is composed of a capsule wall matrix, a plasticizer and water in a weight ratio of 1:0.2˜0.4:0.8˜1.3. The soft capsule of butylphthalide described in the present invention can mask the strong and special flavor of butylphthalide, and overcome the difficulties associated with formulating oily active ingredient into other oral formulation. The disintegration time of the soft capsule satisfies the requirement of Pharmacopoeia of P.R. China.

Find Patent Forward Citations

Li, Jianqing. (2013). Soft capsule of butylphthalide and a process for preparing the same (U.S. Patent No. 8609137). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8609137

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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