The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2013
Filed:
Mar. 18, 2009
Applicants:
Peter Senter, Seattle, WA (US);
Svetlana Doronina, Snohomish, WA (US);
Timothy Bovee, Seattle, WA (US);
Inventors:
Peter Senter, Seattle, WA (US);
Svetlana Doronina, Snohomish, WA (US);
Timothy Bovee, Seattle, WA (US);
Assignee:
Seattle Genetics, Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/42 (2006.01); A61K 38/03 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); G01N 33/48 (2006.01); G01N 33/567 (2006.01); G01N 33/574 (2006.01); G01N 33/577 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); C12N 5/07 (2010.01); C12N 5/09 (2010.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
Abstract
Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.