The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
Dec. 28, 2011
Krzysztof Brzózka, Sieradz, PL;
Wojciech Czardybon, Mikolów, PL;
Aleksandra Sabiniarz, Brzeg Dolny, PL;
Mariusz Millik, Kraków, PL;
Renata Windak, Kraków, PL;
Adrian Zarebski, Busko-Zdrój, PL;
Nicolas Beuzen, Kraków, PL;
Krzysztof Brzózka, Sieradz, PL;
Wojciech Czardybon, Mikolów, PL;
Aleksandra Sabiniarz, Brzeg Dolny, PL;
Mariusz Millik, Kraków, PL;
Renata Windak, Kraków, PL;
Adrian Zarebski, Busko-Zdrój, PL;
Nicolas Beuzen, Kraków, PL;
Selvita S.A., Krakow, PL;
Abstract
A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine and tyrosine kinases and a serine/threonine and tyrosine kinases modulating agent. Novel small-molecule compounds with kinase inhibitory activity, having superior properties as pharmaceutical agents, production method thereof and uses thereof. In particular, new derivatives of tetrahalogenated benzimidazole with serine/threonine and tyrosine kinases inhibitory properties, preferably selected from the group of PIM, HIPK, DYRK, CLK, CDK, FLT, PKG, Haspin, MER, TAO, MNK, TRK kinases which exhibit superior pharmacological actions, and can be useful for the treatment of disease conditions, especially cancers depending on serine/threonine and tyrosine kinases, such as but not limited to leukemias and solid tumors.