The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
Mar. 22, 2010
Applicants:
Pasit Phiasivongsa, Brentwood, CA (US);
Louis C. Sehl, Redwood City, CA (US);
Inventors:
Pasit Phiasivongsa, Brentwood, CA (US);
Louis C. Sehl, Redwood City, CA (US);
Assignee:
Onyx Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 277/24 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to crystalline tripeptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. In addition, the compounds provided herein are immunoproteasome inhibitors and are useful, for example, in the treatment of cancer and autoimmune disease. In some cases, a compound provided herein is a compound of Formula (II):