The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
May. 05, 2010
Kary B. Mullis, Corona del Mar, CA (US);
Jeevalatha Vivekananda, San Antonio, TX (US);
Johnathan Lloyd Kiel, Universal City, TX (US);
Ronald M. Cook, Novato, CA (US);
Kary B. Mullis, Corona del Mar, CA (US);
Jeevalatha Vivekananda, San Antonio, TX (US);
Johnathan Lloyd Kiel, Universal City, TX (US);
Ronald M. Cook, Novato, CA (US);
The United States of America as represented by the Secretary of the Air Force, Washington, DC (US);
Abstract
Methods and compositions for immediately immunizing an individual against any molecule or compound are provided. The present invention is directed to an immunity linker with at least two sites; (1) at least one first binding site that binds to an immune response component in an individual, and (2) at least one second binding site that binds specifically to a desired compound or molecule, the target. The second binding sites are preferably thiolated aptamers that have the benefit of increased stability, resistance to degradation and longer circulating half life. Methods of making and using pharmaceutical compositions including immunity linker molecules having a thiolated aptamer are also provided.