The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
Feb. 06, 2013
Ucb Pharma S.a., Brussels, BE;
Martin Clive Hutchings, Slough Berkshire, GB;
Sarah Catherine Archibald, Slough Berkshire, GB;
Daniel Christopher Brookings, Slough Berkshire, GB;
Jeremy Martin Davis, Slough Berkshire, GB;
James Andrew Johnson, Slough Berkshire, GB;
Barry John Langham, Slough Berkshire, GB;
Judi Charlotte Neuss, Slough Berkshire, GB;
UCB Pharma S.A., Brussels, BE;
Abstract
Novel processes for the preparation of thieno[2,3-b]pyridine derivatives which are substituted in the 2-position by a substituted anilino moiety and intermediates thereto are provided. The compounds prepared by the present processes may be useful, for example, as selective inhibitors of human MEK (MAPKK) enzymes, and are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions. The present processes may offer improved yields, chemical or stereochemical purity, ease of preparation and/or isolation of intermediates and final product, and more industrially useful reaction conditions and workability.