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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8604033 B1

PDFFull Text
Expired
Date of Patent:
Dec. 10, 2013

Filed:

Jan. 14, 2011

Preparation of 4-amino-thiazoles and 3-amino-1,2,4-thiadiazoles and their use as allosteric modulators of metabotropic glutamate receptors

Applicant:

Christelle Boléa, Geneva, CH;

Inventor:

Christelle Boléa, Geneva, CH;

Assignee:

Addex Pharma S.A., Geneva, CH;

Attorney:

Law Offices of Gerard Bilotto, P.C.

Primary Examiner:

Samantha Shterengarts

Assistant Examiner:

Amanda L Aguirre

Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/4439 (2006.01); A61P 25/00 (2006.01); A61P 25/30 (2006.01); A61P 25/24 (2006.01); A61P 25/22 (2006.01); A61P 25/18 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 25/14 (2006.01); A61P 25/08 (2006.01); A61P 27/02 (2006.01); A61P 3/00 (2006.01); A61P 3/10 (2006.01); A61P 1/00 (2006.01); A61P 1/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel compounds of Formula (I), wherein M, P, X, A and (B)are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors—subtype 4 ('mGluR4') which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.

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Boléa, Christelle. (2013). Preparation of 4-amino-thiazoles and 3-amino-1,2,4-thiadiazoles and their use as allosteric modulators of metabotropic glutamate receptors (U.S. Patent No. 8604033). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8604033

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