The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
Oct. 03, 2008
Daniel Kahne, Brookline, MA (US);
Suzanne Walker Kahne, Brookline, MA (US);
Masaatsu Adachi, Nagoya, JP;
Emma Doud, Cambridge, MA (US);
Shinichiro Fuse, Gumma, JP;
Xiaonan Lin, Mendota Heights, MN (US);
Yi Zhang, San Diego, CA (US);
Hirokazu Tsukamoto, Cambridge, MA (US);
Bohdan Ostash, L'viv, UA;
Daniel Kahne, Brookline, MA (US);
Suzanne Walker Kahne, Brookline, MA (US);
Masaatsu Adachi, Nagoya, JP;
Emma Doud, Cambridge, MA (US);
Shinichiro Fuse, Gumma, JP;
Xiaonan Lin, Mendota Heights, MN (US);
Yi Zhang, San Diego, CA (US);
Hirokazu Tsukamoto, Cambridge, MA (US);
Bohdan Ostash, L'viv, UA;
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention provides novel moenomycin analogs as well as pharmaceutical compositions thereof, methods of synthesis, and methods of use in treating an infection by administering an inventive compound to a subject in need thereof. The moenomycin analogs may be prepared synthetically, biosynthetically, or semi-synthetically. The analogs are particularly useful in treating or preventing infections caused by Gram-positive organisms. Certain inventive compounds may have a broader spectrum of coverage, which includes Gram-negative organisms.