The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
Jun. 07, 2010
Applicants:
Bingcheng Wang, Solon, OH (US);
Hui Miao, Rocky River, OH (US);
Inventors:
Bingcheng Wang, Solon, OH (US);
Hui Miao, Rocky River, OH (US);
Assignee:
Case Western Reserve University, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method of detecting malignant progression of neoplastic cells in an animal includes obtaining a sample of neoplastic cells from the animal, determining a level of S897-EphA2 phosphorylation in the neoplastic cells of the samplem, and comparing the determined level of S897-EphA2 phosphorylation in the sample to a control value, wherein an increased level of S897-EphA2 phosphorylation compared to the control value is indicative of malignant progression of the neoplastic cell in the animal.