The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2013

Filed:

Mar. 12, 2008
Applicants:

Jennifer Riggs-sauthier, Huntsville, AL (US);

Lin Cheng, Huntsville, AL (US);

Tacey X. Viegas, Madison, AL (US);

Xuyuan Gu, Madison, AL (US);

Franco J. Duarte, Huntsville, AL (US);

Wen Zhang, Madison, AL (US);

Inventors:

Jennifer Riggs-Sauthier, Huntsville, AL (US);

Lin Cheng, Huntsville, AL (US);

Tacey X. Viegas, Madison, AL (US);

Xuyuan Gu, Madison, AL (US);

Franco J. Duarte, Huntsville, AL (US);

Wen Zhang, Madison, AL (US);

Assignee:

Nektar Therapeutics, San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/02 (2006.01); C07D 401/00 (2006.01); C07D 217/00 (2006.01); C07D 405/00 (2006.01); C07D 213/00 (2006.01); C07D 277/30 (2006.01); C07D 493/00 (2006.01); C07D 307/02 (2006.01); C07F 9/28 (2006.01); C07F 9/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides protease inhibitors that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the protease inhibitors not attached to the water-soluble oligomer.


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