The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Jan. 11, 2012
Juan-miguel Jimenez, Abingdon, GB;
Andrew Miller, Upton Didcot, GB;
Philip Collier, Cambridge, MA (US);
Jeremy Green, Waltham, MA (US);
Albert Dros, Groningen, NL;
Huai Gao, Arlington, MA (US);
Sylvain Hamon, Groningen, NL;
Juan-Miguel Jimenez, Abingdon, GB;
Andrew Miller, Upton Didcot, GB;
Philip Collier, Cambridge, MA (US);
Jeremy Green, Waltham, MA (US);
Albert Dros, Groningen, NL;
Huai Gao, Arlington, MA (US);
Sylvain Hamon, Groningen, NL;
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
The present invention relates to a process for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine in high yield and purity. The present invention also relates to processes for the synthesis of 5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine derivatives. These processes are useful for preparing biologically active compounds, particularly certain GSK-3 inhibitors, or derivatives thereof.