The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2013

Filed:

May. 12, 2009
Applicants:

Eisuke Nozawa, Tokyo, JP;

Ryotaro Ibuka, Tokyo, JP;

Kazuhiro Ikegai, Tokyo, JP;

Keisuke Matsuura, Tokyo, JP;

Tatsuya Zenkoh, Tokyo, JP;

Ryushi Seo, Tokyo, JP;

Susumu Watanuki, Tokyo, JP;

Michihito Kageyama, Tokyo, JP;

Inventors:

Eisuke Nozawa, Tokyo, JP;

Ryotaro Ibuka, Tokyo, JP;

Kazuhiro Ikegai, Tokyo, JP;

Keisuke Matsuura, Tokyo, JP;

Tatsuya Zenkoh, Tokyo, JP;

Ryushi Seo, Tokyo, JP;

Susumu Watanuki, Tokyo, JP;

Michihito Kageyama, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

[Problems] A compound, which is useful as an active ingredient of a pharmaceutical composition, for example, a pharmaceutical composition for treating chronic renal failure and/or diabetic nephropathy, is provided. [Solving Means] The present inventors have conducted extensive studies on a compound having an EP4 receptor antagonistic activity, and confirmed that the amide compound of the present invention has an EP4 receptor antagonistic activity, thereby completing the present invention. The amide compound of the present invention has an EP4 receptor antagonistic activity, and can be used as an active ingredient of a pharmaceutical composition for preventing and/or treating various EP4-related diseases, for example, chronic renal failure and/or diabetic nephropathy, and the like.


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