The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Jun. 05, 2009
Suzanne Walker Kahne, Brookline, MA (US);
Jonathan G. Swoboda, Oil City, PA (US);
Timothy C. Meredith, Plymouth Meeting, PA (US);
Kyungae Lee, Newton, MA (US);
Jennifer Campbell, Brighton, MA (US);
Suzanne Walker Kahne, Brookline, MA (US);
Jonathan G. Swoboda, Oil City, PA (US);
Timothy C. Meredith, Plymouth Meeting, PA (US);
Kyungae Lee, Newton, MA (US);
Jennifer Campbell, Brighton, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention provides Wall Teichoic Acid biosynthesis inhibitors such as compound 1835F03 (targocil) and related synthetic analogs. The invention also provides pharmaceutical compositions thereof and methods for treating bacterial infection and the suppression of growth of bacterial cells by administering a Wall Teichoic Acid biosynthesis inhibitor. The invention is particularly useful for the treatment of Methicillin-resistant(MRSA). The invention further provides procedures for the syntheses of Wall Teichoic Acid biosynthesis inhibitors. The invention also provides methods for the identification of antibacterial therapeutic agents.