The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Jun. 28, 2010
Bandi Parthasaradhi Reddy, Andhra Pradesh, IN;
Kura Rathnakar Reddy, Andhra Pradesh, IN;
Dasari Muralidhara Reddy, Andhra Pradesh, IN;
Rapolu Raji Reddy, Andhra Pradesh, IN;
Bandi Vamsi Krishna, Andhra Pradesh, IN;
Adulla Venkat Narsimha Reddy, Andhra Pradesh, IN;
Bandi Parthasaradhi Reddy, Andhra Pradesh, IN;
Kura Rathnakar Reddy, Andhra Pradesh, IN;
Dasari Muralidhara Reddy, Andhra Pradesh, IN;
Rapolu Raji Reddy, Andhra Pradesh, IN;
Bandi Vamsi Krishna, Andhra Pradesh, IN;
Adulla Venkat Narsimha Reddy, Andhra Pradesh, IN;
Hetero Research Foundation, , IN;
Abstract
4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile is a key intermediate for the preparation of etravirine. The present invention provides a process for preparation of 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile. The present invention also provides a novel process for the preparation of etravirine crystalline form I. The present invention further provides novel crystalline forms of etravirine, processes for their preparation and pharmaceutical compositions comprising them.