The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Mar. 21, 2008
Applicants:
James D. Marks, Kensington, CA (US);
Isin N. Geren, Redwood City, CA (US);
Jianlong Lou, San Bruno, CA (US);
Inventors:
James D. Marks, Kensington, CA (US);
Isin N. Geren, Redwood City, CA (US);
Jianlong Lou, San Bruno, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 39/385 (2006.01); A61K 39/40 (2006.01); A61K 39/42 (2006.01); A01N 37/18 (2006.01); C07K 16/00 (2006.01); C12P 21/08 (2006.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.