The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Jun. 17, 2010
Marc Nazaré, Frankfurt am Main, DE;
Gernot Zech, Frankfurt am Main, DE;
Jochen Goerlitzer, Frankfurt am Main, DE;
Melitta Just, Langen, DE;
Tilo Weiss, Frankfurt am Main, DE;
Gerhard Hessler, Frankfurt am Main, DE;
Werngard Czechtizky, Frankfurt am Main, DE;
Sven Ruf, Frankfurt am Main, DE;
Marc Nazaré, Frankfurt am Main, DE;
Gernot Zech, Frankfurt am Main, DE;
Jochen Goerlitzer, Frankfurt am Main, DE;
Melitta Just, Langen, DE;
Tilo Weiss, Frankfurt am Main, DE;
Gerhard Hessler, Frankfurt am Main, DE;
Werngard Czechtizky, Frankfurt am Main, DE;
Sven Ruf, Frankfurt am Main, DE;
Sanofi, Paris, FR;
Abstract
The present invention relates to compounds of the formula I, whereinR1; R2; Z; A; B; D; Q; J; V; G and M have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong anti-aggregating effect on platelets and thus an anti-thrombotic effect and are suitable, e.g., for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are reversible antagonists of the platelet ADP receptor P2Y12, and can in general be applied in conditions in which an undesired activation of the platelet ADP receptor P2Y12 is present or for the cure or prevention of which an inhibition of the platelet ADP receptor P2Y12 is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.