The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2013

Filed:

Feb. 03, 2010
Applicants:

David Claremon, Maple Glen, PA (US);

Colin Tice, Ambler, PA (US);

Suresh Singh, Kendall Park, NJ (US);

Yuanjie YE, Ambler, PA (US);

Katerina Leftheris, Skillman, NJ (US);

Linghang Zhuang, Chalfont, PA (US);

Inventors:

David Claremon, Maple Glen, PA (US);

Colin Tice, Ambler, PA (US);

Suresh Singh, Kendall Park, NJ (US);

Yuanjie Ye, Ambler, PA (US);

Katerina Leftheris, Skillman, NJ (US);

Linghang Zhuang, Chalfont, PA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5355 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel compounds of an 11 β-HSD1 inhibitor disclosed herein, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11/3-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell.


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