The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Jan. 07, 2011
Karim Senni, Aulnay-sous-Bois, FR;
Farida Gueniche, Rueil-Malmaison, FR;
Myriam Yousfi, Paris, FR;
Florence Fioretti, Paris, FR;
Gaston-jacques Godeau, Antony, FR;
Sylvia Colliec-jouault, Nantes, FR;
Jacqueline Ratiskol, Sainte Luce sur Loire, FR;
Corinne Sinquin, Nantes, FR;
Gérard Raguenes, Locmaria Plouzane, FR;
Anthony Courtois, Saint Renan, FR;
Jean Guezennec, Plouzane, FR;
Karim Senni, Aulnay-sous-Bois, FR;
Farida Gueniche, Rueil-Malmaison, FR;
Myriam Yousfi, Paris, FR;
Florence Fioretti, Paris, FR;
Gaston-Jacques Godeau, Antony, FR;
Sylvia Colliec-Jouault, Nantes, FR;
Jacqueline Ratiskol, Sainte Luce sur Loire, FR;
Corinne Sinquin, Nantes, FR;
Gérard Raguenes, Locmaria Plouzane, FR;
Anthony Courtois, Saint Renan, FR;
Jean Guezennec, Plouzane, FR;
Institut Francais de Recherche pour l'Exploitation de la Mer (IFREMER), Issy les Moulineaux, FR;
Universite Rene Descartes Paris 5, Paris, FR;
Abstract
The invention relates to certain low-molecular weight sulphated polysaccharide derivatives of marine native exopolysaccharides (EPSs) excreted by mesophilic marine bacteria from a deep hydrothermal environment, wherein said derivatives can be obtained by means of a method which comprises a step of free radical depolymerisation of said native EPSs followed by a step of sulphating the resulting depolymerised derivatives. The present invention further relates to the use of said low-molecular weight sulphated polysaccharide derivatives as a wound-healing agent, particularly for preparing pharmaceutical compositions suitable for treating or preventing diseases of the connective tissues and particularly skin and gum tissues. The figure demonstrates how polysaccharide derivative GY 785 DRS according to the invention can stimulate fibroblast proliferation in latticed or reconstructed connective tissues at a concentration of 10 μg (m) g/ml.