The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
May. 08, 2012
Daniel J. Wendt, Walnut Creek, CA (US);
Shinong Long, Milpitas, CA (US);
Sianna Castillo, San Francisco, CA (US);
Christopher P. Price, Kentfield, CA (US);
Mika Aoyagi-scharber, Mill Valley, CA (US);
Michel Claude Vellard, San Rafael, CA (US);
Augustus O. Okhamafe, Concord, CA (US);
Daniel J. Wendt, Walnut Creek, CA (US);
Shinong Long, Milpitas, CA (US);
Sianna Castillo, San Francisco, CA (US);
Christopher P. Price, Kentfield, CA (US);
Mika Aoyagi-Scharber, Mill Valley, CA (US);
Michel Claude Vellard, San Rafael, CA (US);
Augustus O. Okhamafe, Concord, CA (US);
Biomarin Pharmaceutical Inc., Novato, CA (US);
Abstract
The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).