The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Dec. 22, 2008
Wenche Stensen, Kvaloysletta, NO;
Bengt Erick Haug, Tortnes, NO;
Oystein Rekdal, Hvalstad, NO;
John Sigurd Svendsen, Kvaloysletta, NO;
Wenche Stensen, Kvaloysletta, NO;
Bengt Erick Haug, Tortnes, NO;
Oystein Rekdal, Hvalstad, NO;
John Sigurd Svendsen, Kvaloysletta, NO;
Lytix Biopharma AS, Tromso, NO;
Abstract
The present invention relates to a compound of formula (I) AA-AA-AA-X—Y—Z wherein, in any order, 2 of said AA (amino acid) moieties are cationic amino acids and 1 of said AA is an amino acid with a lipophilic R group, the R group having 14-27 non-hydrogen atoms; X is a N atom, which may be substituted by a branched or unbranched C-Calkyl or aryl group which group may incorporate up to 2 heteroatoms selected from N, O and S; Y represents a group selected from —R—R—, —R—R—R— and —R—R—R— wherein Ris C, O, S or N, and Ris C; each of Rand Rmay be substituted by C-Calkyl groups or unsubstituted; and Z is a group comprising 1 to 3 cyclic groups each of 5 or 6 non-hydrogen atoms, 2 or more of the cyclic groups may be fused and one or more of the cyclic groups may be substituted; the Z moiety incorporates a maximum of 15 non-hydrogen atoms; and wherein the bond between Y and Z is a covalent bond between Ror Rof Y and a non-hydrogen atom of one of the cyclic groups of Z. The invention further relates to formulations containing these compounds and their uses in therapy, particularly as antimicrobial or antitumoural agents.