The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8597636 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 03, 2013

Filed:

Jan. 16, 2007
Applicants:

Alan H. Lazarus, Toronto, CA;

Vinayakumar Siragam, Toronto, CA;

Davor Brinc, Toronto, CA;

John Freedman, Toronto, CA;

Andrew R. Crow, Toronto, CA;

Seng Song, Toronto, CA;

Inventors:

Alan H. Lazarus, Toronto, CA;

Vinayakumar Siragam, Toronto, CA;

Davor Brinc, Toronto, CA;

John Freedman, Toronto, CA;

Andrew R. Crow, Toronto, CA;

Seng Song, Toronto, CA;

Assignee:

Canadian Blood Services, Ottawa, Ontario, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 39/395 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of cell-based therapy for treating an autoimmune disease is disclosed. The method is directed at stimulating leukocytes and/or dendritic cells to interrupt autoimmunity in a host. The method provides a Fcγ receptor-specific complex or a complex which results in the co-crosslinking of Fcγ-chains for treating the leukocytes and/or dendritic cells which are in turn used to elicit an autoimmune interruption response in a subject with an autoimmune disease. The Fcγ receptor-specific complex and/or complex which results in the co-crosslinking of Fcγ-chains is used to treat a biological sample comprising leukocytes and/or dendritic cells from a patient, and upon reintroducing said biological sample to the patient, the pre-treated dendritic cells illicit an autoimmune interruption response in vivo.


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Lazarus, Alan. (2013). Method for treating autoimmune diseases and compositions therefor (U.S. Patent No. 8597636). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8597636

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