The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Nov. 19, 2004
Suresh Toby Segaran, Somerville, MA (US);
David Kightley, York, ME (US);
Justin Sun, Norwood, MA (US);
Dexter Pratt, Reading, MA (US);
Maria Fatima Chandra, Framingham, MA (US);
Dundee Navin Chandra, Framingham, MA (US);
Suresh Toby Segaran, Somerville, MA (US);
David Kightley, York, ME (US);
Justin Sun, Norwood, MA (US);
Dexter Pratt, Reading, MA (US);
Selventa, Inc., Cambridge, MA (US);
Abstract
Described are methods, systems and apparatus for hypothesizing a biological relationship in a biological system. A database of biological assertions is provided consisting of biological elements, relationships among the biological elements, and relationship descriptors characterizing the properties of the elements and relationships. A biological element may be selected from the database and a logical simulation may be performed within the biological database, from the selected biological element, through relationship descriptors, along a path defined by potentially causative biological elements to discern a biological element hypothetically responsible for the change in the selected biological element. The logical simulation may be either a backward logical simulation, performed upstream through the relationship descriptors to discern a hypothetical responsible biological element, or a forward logical simulation, performed downstream through the relationship descriptors to discern the extent to which the perturbation generates the observed change in the selected biological element.