The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Dec. 16, 2011
Applicants:
William Reade Kem, Gainesville, FL (US);
Ferenc Soti, Gainesville, FL (US);
Inventors:
William Reade Kem, Gainesville, FL (US);
Ferenc Soti, Gainesville, FL (US);
Assignee:
University of Florida Research Foundation, Inc., Gainesville, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration.