The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Apr. 14, 2009
Mario Varasi, Milan, IT;
Florian Thaler, Gerenzano, IT;
Agnese Abate, Vimodrone, IT;
Giacomo Carenzi, Busto Arsizio, IT;
Ciro Mercurio, Legnano, IT;
Saverio Minucci, Noverasco di Opera, IT;
Mario Varasi, Milan, IT;
Florian Thaler, Gerenzano, IT;
Agnese Abate, Vimodrone, IT;
Giacomo Carenzi, Busto Arsizio, IT;
Ciro Mercurio, Legnano, IT;
Saverio Minucci, Noverasco di Opera, IT;
DAC S.R.L., Milan, IT;
Abstract
This invention is related to new histone deacetylase inhibitors according to the general formula (I) wherein: the dotted line is an optional additional bond; n is zero or an integer from 1 to 4; Ris hydrogen; C-Calkyl, optionally substituted by cycloalkyl, aryl or by heteroaryl; (CO)R; (SO)R; cycloalkyl; aryl; or heteroaryl; Ris C-Calkyl, optionally substituted by aryl or by heteroaryl; aryl; heteroaryl; or (CO)R; X is CH, oxygen or NR; Y is a bond, CHRor NR; Z is oxygen, CRRor C═R; and R, R, R, R, R, R, R, Rand Rare as further defined in the specification; and pharmaceutical acceptable salts thereof.