The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Dec. 16, 2011
P. Jeffrey Conn, Brentwood, TN (US);
Craig W. Lindsley, Brentwood, TN (US);
Shaun R. Stauffer, Brentwood, TN (US);
José Manuel Bartolomé-nebreda, Toledo, ES;
Susana Conde-ceide, Toledo, ES;
Gregor James Macdonald, Beerse, BE;
Han Min Tong, Toledo, ES;
Carrie K. Jones, Nashville, TN (US);
Manuel Jesús Alcázar-vaca, Toledo, ES;
José Ignacio Andrés-gil, Toledo, ES;
Chrysa Malosh, Nashville, TN (US);
P. Jeffrey Conn, Brentwood, TN (US);
Craig W. Lindsley, Brentwood, TN (US);
Shaun R. Stauffer, Brentwood, TN (US);
José Manuel Bartolomé-Nebreda, Toledo, ES;
Susana Conde-Ceide, Toledo, ES;
Gregor James MacDonald, Beerse, BE;
Han Min Tong, Toledo, ES;
Carrie K. Jones, Nashville, TN (US);
Manuel Jesús Alcázar-Vaca, Toledo, ES;
José Ignacio Andrés-Gil, Toledo, ES;
Chrysa Malosh, Nashville, TN (US);
Vanderbilt University, Nashville, TN (US);
Abstract
In one aspect, the invention relates to bicyclic triazole and pyrazole lactams, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.